Translational genetic research of complex diseases

Translational genetic research of complex diseases

the recurrence risk of genetic complex diseases

complex inherited diseases affected by an interaction between collective effects of the genotype at one or multiple loci either to increase or to lower susceptibility to disease, combined with a variety of environmental exposures that may trigger, accelerate, exacerbate, or protect against the disease process. the new aspects of genetic techniques have been opened for diagnosis and analysis of ...

Advances in translational research in neuromuscular diseases.

New therapies developed over the past 3 years for previously intractable diseases of skeletal muscle, neuromuscular junctions, peripheral nerves, and motor neurons are now being incorporated into our standard neuromuscular clinical practice. The past 3 years were also marked by important advances in our understanding of the pathogenesis and pathophysiology of inherited and acquired neuromuscula...

Translational Research in Alzheimer’s and Prion Diseases

Translational neuroscience integrates the knowledge derived by basic neuroscience with the development of new diagnostic and therapeutic tools that may be applied to clinical practice in neurological diseases. This information can be used to improve clinical trial designs and outcomes that will accelerate drug development, and to discover novel biomarkers which can be efficiently employed to ea...

Complex Genetic Diseases

*Please consult the online schedule for this course for the definitive date and time for this lecture. Key Concepts vs Supplementary Information: The syllabus is meant to accompany the lectures and the material covered (other) than that in italics) is considered important to your understanding of the subject. Key items are marked in bold. Supplemental information is marked in italics. Lecture O...